Table I.
Baseline characteristics
| Characteristic | OIT group (n = 20) | Historical control group (n = 20) | P value |
|---|---|---|---|
| Age (y), median (IQR) | 8.0 (6-10) | 6.0 (5-8) | .03 |
| Sex (male), no. (%) | 13 (65%) | 13 (65%) | >.99 |
| Complications, no. (%) | |||
| Bronchial asthma | 15 (75%) | 12 (60%) | .50 |
| Atopic dermatitis | 14 (70%) | 13 (65%) | >.99 |
| Allergic rhinitis | 9 (45%) | 10 (50%) | >.99 |
| Baseline OFC | |||
| Threshold dose (mg), median IQR | 140 (2-250) | 192 (2-250) | >.99 |
| Severity, no. | .56 | ||
| Mild | 3 | 5 | |
| Moderate | 16 | 13 | |
| Severe | 1 | 2 | |
| Total IgE level (IU/mL), median IQR | 751 (492-1432) | 903 (532-2272) | .47 |
| Specific IgE level (kUA/L), median IQR | |||
| Egg white | 45.5 (12.7-94.7) | 46.5 (15.0-66.3) | .57 |
| Ovomucoid | 38.5 (13.5-75.5) | 26.0 (16.2-62.1) | .53 |
| Specific IgG level (mgA/L), median IQR | |||
| Egg white | 6.7 (3.8-15.3) | 3.6 (3.1-6.4) | .09 |
| Ovomucoid | 6.9 (3.3-9.5) | 3.3 (3.0-5.8) | .16 |
| Specific IgG4 level (mgA/L), median IQR | |||
| Egg white | 0.52 (0.18-1.5) | 0.32 (0.16-0.55) | .47 |
| Ovomucoid | 0.46 (0.12-0.97) | 0.20 (0.06-0.47) | .26 |
The Fisher exact test and Mann-Whitney U test were used.
IQR, Interquartile range.