Table I.
Baseline disease characteristics
| Disease characteristic | SoC-ABX464 (n = 339) | SoC-placebo (n = 170) |
|---|---|---|
| SARS-CoV-2 status, no. | 338 | 170 |
| Positive, no. (%) | 338 (100) | 170 (100) |
| Time since onset of symptoms (d) | ||
| no. | 336 | 170 |
| Mean (SD) | 8.1 (20.2) | 6.6 (3.1) |
| Median | 7.0 | 6.0 |
| Risk factors, no. (%) | ||
| Age | 339 | 170 |
| ≥65 y | 98 (28.9) | 50 (29.4) |
| BMI, no. | 334 | 168 |
| ≥30 (kg/m2) | 187 (56.0) | 96 (57.1) |
| Recent history of uncontrolled high blood pressure, no. (%) | 213 (62.8) | 88 (51.8) |
| Treated diabetes (type I or II), no. (%) | 115 (33.9) | 46 (27.1) |
| History of ischemic cardiovascular disease, no. (%) | 0 | 0 |
| No. of concurrent risk factors | ||
| no. | 338 | 169 |
| Mean (SD) | 2.2 (0.9) | 2.1 (0.9) |
| Median | 2.0 | 2.0 |
| SpO2 (visit 1) | ||
| no. | 338 | 170 |
| Mean (SD) | 96.7 (2.0) | 96.9 (2.1) |
| Median | 97.0 | 97.0 |
| WHO ordinal scale (visit 1) | 331 | 168 |
| Not hospitalized, no limitations on activities | 218 (65.9) | 112 (66.7) |
| Not hospitalized, limitation on activities | 46 (13.9) | 22 (13.1) |
| Hospitalized, not requiring supplemental oxygen | 54 (16.3) | 28 (16.7) |
| Hospitalized, requiring supplemental oxygen | 13 (3.9) | 6 (3.6) |