Table 1.
Patients’ and operations’ characteristics by antibiotic group
| Characteristics | Cefuroxime + metronidazole (N = 26,087) | Amoxicillin/clavulanic acid (N = 1835) | p Value |
|---|---|---|---|
| Age, median (IQR) | 68 [58, 77] | 69 [59, 78] | 0.03 |
| Sex, N (%) | |||
| Male | 13,048 (50) | 942 (51.3) | 0.3 |
| Female | 13,039 (50) | 893 (48.7) | |
| ASA score > 2, N (%) | 9254 (35.5) | 650 (35.4) | 0.9 |
| Rectal procedures, N (%) | 1654 (6.3) | 134 (7.3) | 0.1 |
| Elective procedures, N (%) | 22,946 (88.0) | 1595 (86.9) | 0.2 |
| Laparoscopic surgery, N (%) | 13,975 (53.6) | 912 (49.7) | 0.001 |
| Reoperation for a non-infectious complication, N (%) | 1376 (5.3) | 100 (5.4) | 0.8 |
| Operation duration in minutes, median (IQR) | 169 [122, 227] | 162 [117, 229] | 0.001 |
| Timing of antibiotic prophylaxis in minutes, median (IQR) | − 35 [− 50, − 20] | − 36 [− 55, − 20] | 0.001 |
| Operation duration > 75th percentile, N (%) | 11,361 (43.6) | 746 (40.7) | 0.02 |
| Operations by hospital size, N (%) | |||
| < 200 beds | 10,579 (40.6) | 649 (35.4) | < 0.001 |
| 200–499 beds | 10,447 (40.0) | 1063 (57.9) | |
| ≥ 500 beds | 5061 (19.4) | 123 (6.7) |
*The inclusion of colon surgery in the surveillance system is mandatory. Hospitals must choose at least 2 other operations from a catalogue of 13 that includes rectal surgery