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. 2023 Aug 30;66(17):12324–12341. doi: 10.1021/acs.jmedchem.3c00845

Table 1. Half-Life of Elimination of 5FU for Phenylacrylate Derivatives.

cpd. R t1/2 (h)
11 F 3.0
12 Cl 2.9
13 OMe 36
14 CN 2.5
17 NO2 0.1