Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
n.d.: not determined.
CYP3A4 inhibition: IC50 without preincubation/IC50 after 30 min preincubation.
tPSA value does not reflect the actual polar surface area as the algorithm simply sums up the polar surface of precalculated functional groups and does not take into account intramolecular hydrogen bonds.
