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. 2020 Jun 25;45(2):131–141. doi: 10.1247/csf.20010

Table I.

Phenotype of Blvra-knockout mice

Tissue Phenotypes Strain and target Refs
Liver Hepatic lipid accumulation under a high fat diet. Enhanced fasting hyperglycemia and hyperinsulinemia. C57BL/6J
Deletion of Exon 2
Hinds et al.
Whole body Enhanced endogenous oxidative stress: higher concentrations of cholesteryl ester hydroperoxides and oxidized peroxiredoxin 2. C57BL/6J
Deletion of Exon 3
Chen et al.
Whole body Enhanced sensitivity to oxidative stress in neurons. C57BL/6J
Deletion of Exon 3
Vasavda et al.
Myeloid cells Enhanced chemokine expression and chemotaxis in myeloid cells. 129S/C57BL/6J
Deletion of exons 4 and 5
Bisht et al.