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. 2023 Sep 20;18(9):e0291881. doi: 10.1371/journal.pone.0291881

Table 3. MCIDs for Liverpool Osteoarthritis in Dogs and Canine Orthopedic Index.

Anchor-based Distribution-based
CROM AC CD MDC ROC Curve (AUC) Effect size SEM
LOAD -8.6 -9.1 -4.4 -2.5 (0.872) ±1.6 ±4.2
COI Stiffness -4.0 -4.2 -1.2 -1.0 (0.777) ±0.7 ±1.1
Function -4.1 -4.3 -1.4 -0.5 (0.774) ±0.8 ±1.6
Gait -4.7 -4.9 -2.0 -1.5 (0.770) ±1.1 ±2.7
QOL -3.2 -3.3 -1.4 -0.5 (0.768) ±0.6 ±1.8
Overall -16.1 -16.6 -14.5 -4.5 (0.778) ±2.4 ±2.3

AC–Average Change; AUC–Area under the curve; CD–Change difference; MDC–Minimum detectable change; ROC—Receiver operating characteristic; SEM—standard error of measurement.