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. 2023 May 24;325(1):F105–F120. doi: 10.1152/ajprenal.00269.2022

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Figure 2. — All components of the histaminergic system are abundantly expressed in the human kidney. Images represent immunohistochemistry of cortical glomeruli (A) and cortical tubular (B) and medullary (C) regions of human kidney samples. Top: representative images showing histamine decarboxylase (HDC), histamine N-methyltransferase (HNMT), and diamine oxidase (DAO) expression. Bottom: representative images showing histamine receptor (HR)1, HR2, HR3, and HR4 expression. Magnification: ×20. Scale bars = 50 µm. Scale bars shown in the negative control image apply to all images within the same group. The brown coloration represents expression.