Renal histamine receptor (HR) abundance following acute treatment with ranitidine (RAN). A–D, top: representative Western blots probed for HR1 (A), HR2 (B), HR3 (C), and HR4 (D) in renal cortex samples of vehicle (VEH)- and RAN-treated Dahl salt-sensitive rats fed a high-salt diet with the Ponceau-stained membrane representing total protein shown below the antibody probed-membrane. A–D, bottom: densitometric analysis of the Western blots; n = 6 for VEH treatment and 8 for RAN treatment. Boxes indicate means ± SE; whiskers are SDs. One-way ANOVA with a Holm-Sidak post hoc test was used for statistical analysis; a.u. arbitrary units.