Table 1.

Basic biometric parameters for vehicle- vs. ranitidine-treated groups of high-salt diet-fed Dahl salt-sensitive rats

	Vehicle		Ranitidine
	Mean	SE	Mean	SE
Total body weight, g	355	7.3	364	8.1
Two kidneys-to-body weight ratio, mg/g	9.8	0.35	9.7	0.27
Heart weight-to-body weight ratio, mg/g	3.8	0.12	3.8	0.09
Plasma Na+, mM	145	0.51	146	0.36
Plasma K+, mM	3.2	0.08	3.4	0.08
Plasma Cl−, mM	106	0.59	107	0.57
Glomerular filtration rate, mL/min/100 g)	0.8	0.07	0.8	0.07

n = 7–8 for vehicle treatment and 10 for ranitidine treatment. The following parameters were assessed: total body weight, two kidneys-to-body weight ratio, heart weight-to-body weight ratio, plasma Na⁺, plasma K⁺, and plasma Cl⁻. As a measure of renal function for high-salt diet-fed Dahl salt-sensitive rats for vehicle vs. ranitidine treatment, glomerular filtration rate was assessed as the filtration rate of FITC-inulin.