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Lactobacillus acidophilus (LA) does not interfere with metformin-induced effect on blood glucose. A: treatment scheme of LA and metformin (Met). Changes in body weight (B) and blood glucose levels (C) in db/db mice treated with PBS (Con), LA, metformin (M), or metformin + LA (M + LA) are shown. **P < 0.01; ****P < 0.0001; ns, not significant.
