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. 2023 Jul 25;47(10):1000–1007. doi: 10.1038/s41366-023-01350-0

Table 3.

Statistically significant interaction analyses with sex, age, body mass index, cardiorespiratory fitness and objectively measured physical activity and sedentary time.

Outcome Explanatory variable n P-value for interaction Category 1 β (95% CI) Category 2 β (95% CI)
Sex Male Female
VAT (L) CRF (mL∙kg1∙min1)bc 121 0.024 −0.04 (−0.08 to 0.01) −0.01 (−0.03 to 0.01)
VAT (L) Sedentary time (per 30 min)ac 121 0.074 −0.01 (−0.14 to 0.11) 0.06 (0.02 to 0.10)
Age < 37 years ≥ 37 years
Adipo-IR (AU) Sedentary time (per 30 min)ac 129 0.041 0.33 (−1.29 to 1.95) 1.09 (0.40 to 1.78)
BMI <26.1kg ∙ m-2 26.1kg ∙ m-2
Adipo-IR (AU) Sedentary time (per 30 min)ac 129 0.063 0.23 (−1.24 to 1.70) 1.18 (0.53 to 1.84)
ScAT (L) CRF (mL∙kg1∙min1)bc 121 0.068 −0.10 (−0.28 to 0.09) −0.24 (−0.33 to −0.15)
Cardiorespiratory fitness <40.1mL∙kg-1∙min-1 40.1mL∙kg-1∙min-1
Adipo-IR (AU) Sedentary time (per 30 min)ac 129 0.039 1.08 (−0.55 to 2.71) 0.21 (−0.47 to 0.89)

Data are presented as P-values for the interaction term and as β-coefficients (95% confidence intervals) for categorical variables and variables stratified using the median split.

Adjusted for study, sex, ethnicity, age, device wear time, BMI, glucose, TAG, HDL, interaction term and aCRF, bsedentary time or cMVPA.

Adipo-IR adipose tissue insulin resistance index, BMI body mass index, CRF cardiorespiratory fitness, HDL high-density lipoprotein, MVPA moderate-to-vigorous physical activity, ScAT subcutaneous abdominal adipose tissue, TAG triacylglycerol, VAT visceral adipose tissue.