Table 3.

Effect of T. erecta leaves fractions (ethyl acetate, butanol) & acacetin 7-O-glucoside on each of the following: liver enzymes

Liver enzymes	Group 1 Control	Group 2 Den [55 mg/kg]	Group 3 Den + DoX [10 mg/kg]	Group 4 Den + EB [50 mg/kg]	Group 5 Den + EE [50 mg/kg]	Group 6 Acacetin 7-O-glucoside [0.44 mg/ml]
ALT U/l	19 ± 1.2	29 ± 2.6*	14 ± 1.4#	25 ± 1*#	16 ± 2.4#	18.3 ± 0.33#
AST U/l	48 ± 0.5	80 ± 0.8*	59 ± 1.8#	74 ± 1.5*#	74 ± 1.5*#	50.5 ± 0.8#
ALP U/l	102 ± 6	141 ± 2*	120 ± 1.2#	137 ± 1.5*#	130 ± 2.6*#	98 ± 0.57

Data are represented as mean ± SEM (n = 6). * p ˂ 0.05 vs. normal control, # p ˂ 0.05 vs Den, *# > 0.05, p ˂ 0.05 vs Den + Dox. Statistical analysis was done using one-way ANOVA followed by the Dunnett test as a multiple comparison test. ALT, analine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; IL-Iβ, interleukin 1 beta; Caspase-3, cysteine-aspartic protease-3; Rat TNF-α, rat tumor necrosis factor-alpha; MDA, malondialdehyde; GSH, glutathione; Dox, doxorubicin; EB, erecta butanol; EE, erecta ethylactate. (*significant from -ve control gp &# significant from +ve control)