Table 5.

Effect of T. erecta leaves fractions (ethyl acetate, butanol) & acacetin 7-O-glucoside on each of the following: oxidative stress markers

Oxidative stress markers	Group 1 Control	Group 2 Den [55 mg/kg]	Group 3 Den + DoX [10 mg/kg]	Group 4 Den + EB [50 mg/kg]	Group 5 Den + EE [50 mg/kg]	Group 6 Acacetin 7-O-glucoside [0.44 mg/ml]
MDA nmol/g tissue	24 ± 0.5	50 ± 0.9*	30 ± 0.4#	34 ± 0.7#	33.6 ± 0.5#	36 ± 1.5
GSH nmol/g tissue	13 ± 0.2	6.5 ± 0.2*	8.4 ± 0.05#	7.8 ± 0.05#		10.6 ± 0.3

Data are represented as mean ± SEM (n = 6). *p <0.05 vs. normal control, #p <0.05 vs Den, *#p <0.05 vs Den + Dox. Statistical analysis was done using one-way ANOVA followed by the Dunnett test as a multiple comparison test. ALT, analine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; IL-Iβ, interleukin 1 beta; Caspase-3, cysteine-aspartic protease-3; Rat TNF-α, rat tumor necrosis factor-alpha; MDA, malondialdehyde; GSH, glutathione; Dox, doxorubicin; EB, erecta butanol; EE, erecta ethylactate. (* significant from -ve control &# significant from +ve control)