Fig. 4.

Strain measures and their correlations to DTI-derived HA. Left panel shows the three planes from MR imaging, with the whole plaque delineated in black, and the first-eigenvector map of one mechanically tested specimen overlaid. A 3D visualisation of the plaque and strip is presented below them with a schematic showing where the helical angle, alpha, is calculated by the z- and x-components of the first-eigenvector. Right panel: A Engineering strain from grip-to-grip (Grip), the gauge length from DIC (DIC-G), and local failure on DIC (DIC-L). Significance determined by repeated measures one-way ANOVA with Tukey’s post hoc multiple comparisons; ****p < 0.0001. Correlations between DTI-derived HA and B Grip-to-grip strain, C DIC gauge strain, and D DIC local strain.