Table 1.
Characteristics of participants.
| Variables | Cohort (n = 125) | Hypertensive (n = 42) | Normotensive (n = 83) | P-value |
|---|---|---|---|---|
| Age (years), mean ± SD | 49.0 ± 17.0 | 55.7 ± 14.5 | 45.3 ± 17.2 | 0.001 |
| Female, n (%) | 77 (62%) | 24 (57%) | 53 (64%) | 0.56 |
| Race, n (%) | ||||
| White | 76 (61%) | 23 (55%) | 53 (64%) | 0.51 |
| Black/African American | 30 (24%) | 12 (29%) | 18 (22%) | – |
| Asian | 17 (14%) | 7 (16%) | 10 (12%) | – |
| Ethnicity, n (%) | ||||
| Hispanic/Latino | 18 (14%) | 5 (16%) | 13 (16%) | 0.78 |
| BMI (kg/m2), mean ± SD | 27.8 ± 4.2 | 26.6 ± 5.6 | 0.15 | |
| Serum creatinine (mg/dL), mean ± SD | 0.84 ± 0.17 | 0.82 ± 0.16 | 0.43 | |
| Fasting glucose (mg/dL), mean ± SD | 95.2 ± 12.5 | 92.5 ± 12.9 | 0.32 | |
| eGFR (mL/min/1.73m2), mean ± SD | 91.3 ± 19.2 | 99.6 ± 19.4 | 0.05 | |
| Office BP (mmHg), mean ± SD | ||||
| Seated systolic BP | 134 ± 20 | 120 ± 9 | < 0.001 | |
| Seated diastolic BP | 80 ± 11 | 75 ± 5 | 0.002 | |
| Standing systolic BP | 136 ± 24 | 121 ± 9 | < 0.001 | |
| Standing diastolic BP | 85 ± 13 | 78 ± 6 | < 0.001 | |
| Office HR (bpm), mean ± SD | ||||
| Sitting HR | 71 ± 11 | 71 ± 11 | 0.82 | |
| Standing HR | 80 ± 13 | 78 ± 12 | 0.43 | |
| Ambulatory BP (mmHg), mean ± SD | ||||
| 24-h SBP, mean ± SD | 130 ± 12 | 111 ± 7 | < 0.001 | |
| 24-h DBP, mean ± SD | 78 ± 7 | 68 ± 4 | < 0.001 | |
| Daytime SBP, mean ± SD | 134 ± 13 | 115 ± 7 | 0.002 | |
| Daytime DBP, mean ± SD | 81 ± 8 | 72 ± 5 | < 0.001 | |
| Nighttime SBP, mean ± SD | 121 ± 14 | 102 ± 13 | < 0.001 | |
| Nighttime DBP, mean ± SD | 70 ± 7 | 61 ± 5 | < 0.001 | |
| Ambulatory HR (bmp), mean ± SD | ||||
| 24-h HR | 75 ± 9 | 70 ± 9 | 0.002 | |
| Daytime HR | 77 ± 9 | 72 ± 9 | 0.004 | |
| Nighttime HR | 71 ± 10 | 64 ± 10 | 0.001 | |
Categorical data are presented as number and percentage and continuous data are presented as mean and standard deviation. P < 0.05 was considered statistically significant.
BMI body mass index, BP blood pressure, eGFR estimated glomerular filtration rate, HR heart rate, SD standard deviation.