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. 2023 Sep 20;80(10):297. doi: 10.1007/s00018-023-04944-z

Table 1.

A brief summary of ECM molecules (as proposed by Naba et al. [12])

Domain Category Function Notable examples
Core matrisome Collagens Structural Collagen I, Collagen IV
Glycoproteins Structural, functional, signaling Laminins, Emilins, Tenascins
Proteoglycans Functional, signaling Versican, Perlecan, Biglycan
Matrisome-associated ECM regulators Regulatory (ECM-remodeling enzymes, crosslinkers, proteases, regulators etc.) Lysyl oxidases, Serpins, Cathepsins
Secreted factors Known or suspected to bind core ECM proteins CXCLs, Angiopoietins, S100A