Table 2.

Left–right difference in the volume and volume ratio of the segmented regions

	Left	Right	Difference	p value
Total brain (mL)	551.1 ± 56.9	549.2 ± 56.7	1.9 ± 7.2	0.705
Frontal cortex (mL)	82.3 ± 9.4	85.7 ± 10.0	−3.5 ± 2.7	0.004
Parietal cortex (mL)	57.7 ± 6.5	57.3 ± 6.4	0.4 ± 1.9	0.674
Temporal cortex (mL)	59.4 ± 7.1	59.1 ± 7.2	0.2 ± 2.0	0.738
Occipital cortex (mL)	27.5 ± 3.6	28.6 ± 4.0	−1.0 ± 2.2	0.040
Cerebral white matter (mL)	208.8 ± 25.3	209 ± 25.6	−0.2 ± 3.0	0.943
Cerebellum (mL)	68.4 ± 7.2	67.4 ± 6.6	1.0 ± 1.6	0.201
Insula cortex (mL)	6.3 ± 0.7	6.5 ± 0.7	−0.3 ± 0.3	0.002
Hippocampus (mL)	3.3 ± 0.3	3.5 ± 0.4	−0.2 ± 0.1	< 0.001
Basal ganglia (mL)	7 ± 0.8	6.6 ± 0.8	0.4 ± 0.3	< 0.001
Limbic system (mL)	18.1 ± 2.1	15.1 ± 1.8	3.0 ± 1.2	< 0.001
Lateral ventricle (mL)	12.3 ± 6.2	10.3 ± 5.6	2.0 ± 2.3	< 0.001
Total brain (volume ratio, %)	38.2 ± 1.7	38.0 ± 1.7	0.1 ± 0.5	0.607
Frontal cortex (%)	5.7 ± 0.4	5.9 ± 0.4	−0.2 ± 0.2	< 0.001
Parietal cortex (%)	4.0 ± 0.3	4.0 ± 0.3	0.03 ± 0.13	0.444
Temporal cortex (%)	4.1 ± 0.3	4.1 ± 0.3	0.01 ± 0.14	0.744
Occipital cortex (%)	1.9 ± 0.2	2.0 ± 0.2	−0.07 ± 0.15	0.003
Cerebral white matter (%)	14.5 ± 1.0	14.5 ± 1.0	−0.01 ± 0.21	0.880
Cerebellum (%)	4.7 ± 0.4	4.7 ± 0.4	0.07 ± 0.11	0.119
Insula cortex (%)	0.43 ± 0.03	0.45 ± 0.03	−0.02 ± 0.02	< 0.001
Hippocampus (%)	0.23 ± 0.01	0.25 ± 0.02	−0.02 ± 0.01	< 0.001
Basal ganglia (%)	0.49 ± 0.04	0.46 ± 0.04	0.03 ± 0.02	< 0.001
Limbic system (%)	1.3 ± 0.1	1.1 ± 0.1	0.2 ± 0.1	< 0.001
Lateral ventricle (%)	0.8 ± 0.4	0.7 ± 0.4	0.1 ± 0.2	< 0.001

p-value of the right–left difference based on the Mann–Whitney–Wilcoxon test