Table 1.
Activation potential for toll-like receptor 9 (TLR9)40
| AAV DNA vector | TLR9 activation potential (KTLR9) | Activation (+/−) |
|---|---|---|
| CK8e-Cas9-FS | 19.7 | ++ |
| CK8e-Cas9 | 19.7 | ++ |
| CK8e-μDYS | 12.8 | + |
| AAV2 WT genome | 26.0 | +++ |
| Human genome | 1.0 | – |
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