Table 1:
Diagnostic performance of four different antigens (hydatid cyst fluid [HCF], lyophilized hydatid cyst fluid [LHCF], antigen B [AgB] and lyophilized antigen B [LAgB]) in IgG ELISA for sero-diagnosis of liver cystic echinococcosis (CE)
| Variable | Type of Antigen | ||||
|---|---|---|---|---|---|
| HCF [Positive/total (No/%)] | LHCF [Positive/total (No/%)] | AgB [Positive/total (No/%)] | LAgB [Positive/total (No/%)] | ||
| Type of sera | Pathologically positive sera | 30/33 (90.9) | 32/33 (96.97) | 27/33 (84.38) | 27/33 (84.38) |
| Sera of healthy people | 2/60 (3.33) | 3/60 (5) | 1/60 (1.66) | 1/60 (1.66) | |
| Sera of other diseases | 4/48 (8.33) | 5/48 (10.42) | 7/48 (14.58) | 4/48 (8.33) | |
| Statistical analysis | Sensitivity Value / 95% CI | 90.91/75.67 to 98.08 | 96.97/84.24 to 99.92 | 81.82/64.54 to 93.02 | 81.82/64.54 to 93.02 |
| Specificity Value / 95% CI | 94.44/88.30 to 97.93 | 92.59/85.93 to 96.75 | 92.59/85.93 to 96.75 | 95.37/89.53 to 98.48 | |
| Positive Likelihood Ratio Value / 95% CI | 16.36/ 7.46 to 35.88 | 13.09/6.70 to 25.57 | 11.05/ 5.56 to 21.93 | 17.67/ 7.40 to 42.22 | |
| Negative Likelihood Ratio Value / 95% CI | 0.10/0.03 to 0.28 | 0.03/0.00 to 0.23 | 0.20/0.10 to 0.41 | 0.19/0.09 to 0.39 | |
| Disease prevalence Value / 95% CI | 23.40/16.69 to 31.27 | 23.40/16.69% to 31.27 | 23.40/16.69 to 31.27 | 23.40/16.69 to 31.27 | |
| Positive Predictive Value Value / 95% CI | 83.33/69.52 to 91.64 | 80.00/67.19 to 88.65 | 77.14/62.96 to 87.02 | 84.38/ 9.33 to 92.81 | |
| Negative Predictive Value Value / 95% CI | 97.14/92.03 to 99.01 | 99.01/93.55 to 99.86 | 94.34/88.97 to 97.18 | 94.50/89.26 to 97.26 | |
| Accuracy Value / 95% CI | 93.62/88.23 to 97.04 | 93.62/88.23 to 97.04 | 90.07/83.90 to 94.46 | 92.20/86.47 to 96.04 | |