Table 3.
Coordinately expressed SM gene clusters identified by MIDDAS analysis.
| Strain | Cluster start | Cluster end | # of genes | SM backbone gene in the cluster | Predicted metabolite | # of conserved species |
|---|---|---|---|---|---|---|
| A. fumigatus | Afu2g17515 | Afu2g17600 | 8 | Afu2g17600 (pksP) | DHN-melanin | 9 (BGC4) |
| Afu4g14460 | Afu4g14580 | 13 | Afu4g14560 (tpcC) | Trypacidin | Partry-conserved: 7 | |
| Afu6g09600 | Afu6g09745 | 16 | Afu6g09610, Afu6g09660 (gliP) | Gliotoxin | 9 (BGC8) | |
| Afu8g00370 | Afu8g00580 | 21 | Afu8g00370 (fmaB), Afu8g00490, Afu8g00540 (psoA) | Fmagilin, pseurotin | Partry-conserved: 6, 5, 1 | |
| N. fischeri | NFIA_005560 | NFIA_005620 | 7 | NFIA_005590 (sidD) | Fusarinine C, triacetylfusarinine C | Partry-conserved: 8 |
| NFIA_008100 | NFIA_008190 | 10 | NFIA_008170 (sidC) | Ferricrocin | 9 (BGC2) | |
| NFIA_062240 | NFIA_062290 | 6 | NFIA_062250 | Partry-conserved: 2 | ||
| NFIA_064390 | NFIA_064420 | 4 | NFIA_064400 (hasD) | Hexadehydroastechrome | Partry-conserved: 8 | |
| NFIA_093690 | NFIA_093740 | 6 | NFIA_093690 (ftmA) | Fumitremorgins | Partry-conserved: 5 | |
| NFIA_100450 | NFIA_100520 | 8 | NFIA_100520 (pyr2) | Pyripyropene A | Partry-conserved: 5 | |
| A. lentulus | Alt_003617-T1 | Alt_003624-T1 | 8 | Alt_003621-T1 (hasD) | Hexadehydroastechrome | Partry-conserved: 8 |
| Alt_006925-T1 | Alt_006934-T1 | 10 | Alt_006934-T1 (gliP) | Gliotoxin | 9 (BGC8) | |
| Alt_007753-T1 | Alt_007763-T1 | 11 | Alt_007763-T1 (terA), Alt_007762-T1 (terB) | Terrein | Partry-conserved: 3 | |
| A. udagawae | Aud_002752-T1 | Aud_002766-T1 | 14 | Aud_002754-T1 (sidE), Aud_002763-T1 (sidD) | Fumarylalanine, fusarinine C, triacetylfusarinine C | 9 (BGC6) |
| Aud_003574-T1 | Aud_003581-T1 | 8 | Aud_003577-T1 (hasD) | Hexadehydroastechrome | Partry-conserved: 8 | |
| Aud_004514-T1 | Aud_004525-T1 | 12 | Aud_004523-T1 (gliP) | Gliotoxin | 9 (BGC8) | |
| Aud_008852-T1 | Aud_008859-T1 | 8 | Aud_008854-T1 | Partry-conserved: 3 | ||
| Aud_009320-T1 | Aud_009344-T1 | 25 | Aud_009335-T1 | Partry-conserved: 2 | ||
| A. viridinutans | Avi_000056-T1 | Avi_000060-T1 | 5 | Avi_000055-T1, (pksP) | DHN-melanin | 9 (BGC4) |
| Avi_003609-T1 | Avi_003616-T1 | 8 | Avi_003616-T1 (vdtA) | Viriditoxin | Partry-conserved: 3 | |
| Avi_003634-T1 | Avi_003641-T1 | 8 | Avi_003638-T1 | Partry-conserved: 2 | ||
| Avi_005751-T1 | Avi_005756-T1 | 6 | Avi_005753-T1 (hasD) | Hexadehydroastechrome | Partry-conserved: 8 | |
| Avi_005973-T1 | Avi_005983-T1 | 11 | Avi_005973-T1 | Partry-conserved: 3 | ||
| Avi_007490-T1 | Avi_007496-T1 | 7 | Avi_007494-T1 | Partry-conserved: 2 | ||
| Avi_009093-T1 | Avi_009095-T1 | 3 | Avi_009095-T1 (sidC) | Ferricrocin | 9 (BGC2) | |
| Avi_002834-T1 | Avi_002841-T1 | 8 | Avi_002834-T1 (ftmA) | Fumitremorgin | Partry-conserved: 5 | |
| Avi_003350-T1 | Avi_003368-T1 | 18 | Avi_003364-T1 (nscA/fccA), Avi_003357-T1 | Neosartoricin/fumicycline A | 9 (BGC9) |