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. 2023 Sep 21;21:248. doi: 10.1186/s12964-023-01281-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Exosomal lncRNA Mir100hg secreted by LLC-SD enhanced the metastatic ability of LLC. A The efficiency of Mir100hg Knockdown in LLC-SD; B Expression of Mir100hg in LLC-SD-shMir100hg-Exosomes; C Expression of Mir100hg in LLC after co-cultured with LLC-SD-shMir100HG-exosomes for 20h; D The migration and invasion ability of LLC after co-culturing with LLC-SD-shMir100hg-exosomes for 20 h; E Column chart of migration and invasion cells; F Schematic representation of exosome animal experiments; G Tumor metastasis in the lung and chest and abdominal wall was observed in mice after tail vein injection of different cell-derived exosomes (green). (*p < 0.05, **p < 0.01, ***p < 0.001)