Table 2.
Association between adiposity indicators and obstructive sleep apnea
| Adiposity indicators | N | Effect | |||
|---|---|---|---|---|---|
| Non-OSA group | OSA group | Unadjusted OR (95% CI) | Adjusted OR (95% CI)a | Adjusted OR (95% CI)b | |
| NC, cm | |||||
| Q1 (≤ 32.10) | 2341 | 155 | 1.00 | 1.00 | 1.00 |
| Q2 (> 32.10 ~ ≤ 34.20) | 2197 | 309 | 2.12 (1.74, 2.60) | 2.09 (1.71, 2.56) | 1.40 (1.14, 1.73) |
| Q3 (> 34.20 ~ ≤ 36.60) | 1929 | 396 | 3.10 (2.56, 3.78) | 3.12 (2.55, 3.83) | 1.61 (1.30, 2.01) |
| Q4 (> 36.60) | 1640 | 766 | 7.05 (5.89, 8.50) | 7.49 (6.06, 9.30) | 2.29 (1.78, 2.97) |
| P for trend | < 0.001 | 0.553 | < 0.001 | ||
| Every 1-unit increment | 1.25 (1.23, 1.27) | 1.29 (1.26, 1.32) | 1.13 (1.10, 1.16) | ||
| BF%, % | |||||
| Q1 (≤ 26.10) | 2073 | 381 | 1.00 | 1.00 | 1.00 |
| Q2 (> 26.10 ~ ≤ 31.00) | 2041 | 390 | 1.04 (0.89, 1.21) | 2.00 (1.69, 2.36) | 1.26 (1.06, 1.50) |
| Q3 (> 31.00 ~ ≤ 35.10) | 2125 | 340 | 0.87 (0.74, 1.02) | 4.13 (3.31, 5.17) | 1.97 (1.55, 2.51) |
| Q4 (> 35.10) | 1868 | 515 | 1.50 (1.30, 1.74) | 8.56 (6.74, 10.91) | 2.65 (2.01, 3.48) |
| P for trend | < 0.001 | < 0.001 | 0.029 | ||
| Every 1-unit increment | 1.03 (1.02, 1.04) | 1.17 (1.15, 1.18) | 1.09 (1.07, 1.10) | ||
| WHR | |||||
| Q1 (≤ 0.83) | 2303 | 132 | 1.00 | 1.00 | 1.00 |
| Q2 (> 0.83 ~ ≤ 0.88) | 2101 | 331 | 2.75 (2.23, 3.40) | 2.39 (1.94, 2.97) | 1.68 (1.35, 2.09) |
| Q3 (> 0.88 ~ ≤ 0.93) | 1952 | 482 | 4.31 (3.53, 5.29) | 3.45 (2.81, 4.25) | 1.93 (1.56, 2.41) |
| Q4 (> 0.93) | 1751 | 681 | 6.79 (5.59, 8.29) | 5.02 (4.10, 6.19) | 2.15 (1.73, 2.71) |
| P for trend | < 0.001 | < 0.001 | < 0.001 | ||
| Every 0.01-unit increment | 1.08 (1.07, 1.09) | 1.07 (1.06, 1.08) | 1.03 (1.02, 1.04) | ||
| VAI | |||||
| Q1 (≤ 5.00) | 2662 | 128 | 1.00 | 1.00 | 1.00 |
| Q2 (> 5.00 ~ ≤ 8.00) | 2430 | 317 | 2.71 (2.20, 3.37) | 2.58 (2.09, 3.20) | 1.91 (1.54, 2.40) |
| Q3 (> 8.00 ~ ≤ 11.00) | 1660 | 381 | 4.77 (3.88, 5.90) | 4.32 (3.49, 5.38) | 2.54 (2.00, 3.24) |
| Q4 (> 11.00) | 1355 | 800 | 12.28 (10.11, 15.02) | 10.91 (8.85, 13.54) | 4.58 (3.49, 6.02) |
| P for trend | < 0.001 | 0.302 | < 0.001 | ||
| Every 1-unit increment | 1.21 (1.20, 1.23) | 1.20 (1.19, 1.22) | 1.14 (1.12, 1.16) | ||
| LAP | |||||
| Q1 (≤ 18.02) | 2275 | 160 | 1.00 | 1.00 | 1.00 |
| Q2 (> 18.02 ~ ≤ 31.12) | 2099 | 333 | 2.26 (1.85, 2.75) | 2.18 (1.79, 2.67) | 1.43 (1.16, 1.76) |
| Q3 (> 31.12 ~ ≤ 51.60) | 1967 | 466 | 3.37 (2.79, 4.08) | 3.32 (2.74, 4.04) | 1.79 (1.46, 2.21) |
| Q4 (> 51.60) | 1766 | 667 | 5.37 (4.48, 6.47) | 5.38 (4.47, 6.51) | 2.24 (1.81, 2.77) |
| P for trend | < 0.001 | < 0.001 | < 0.001 | ||
| Every 10-unit increment | 1.07 (1.06, 1.09) | 1.07 (1.06, 1.09) | 1.02 (1.01, 1.03) | ||
| RMR, Kcal/day | |||||
| Q1 (≤ 1163.00) | 2282 | 154 | 1.00 | 1.00 | 1.00 |
| Q2 (> 1163.00 ~ ≤ 1285.00) | 2163 | 282 | 1.93 (1.58, 2.38) | 2.05 (1.67, 2.52) | 1.82 (1.47, 2.24) |
| Q3 (> 1285.00 ~ ≤ 1467.00) | 1969 | 451 | 3.39 (2.81, 4.13) | 4.16 (3.40, 5.10) | 3.31 (2.69, 4.09) |
| Q4 (> 1467.00) | 1693 | 739 | 6.47 (5.39, 7.80) | 11.19 (8.81, 14.28) | 7.43 (5.75, 9.64) |
| P for trend | < 0.001 | < 0.001 | 0.044 | ||
| Every 10-unit increment | 1.03 (1.02, 1.04) | 1.04 (1.03, 1.05) | 1.04 (1.03, 1.05) | ||
Abbreviation: NC Neck circumference, BF % Body fat percentage, WHR Waist hip ratio, VAI Visceral adiposity index, LAP The lipid accumulation product, RMR The resting metabolic rate
aAdjustment for age, sex, marital status, education, smoking, alcohol drinking, fruit intake, vegetable intake, work intensity, and leisure-time physical activity
bFurther adjustment for NC, WHR, BF%, VAI, LAP, and RMR