Skip to main content

View full-text article in PMC

. 2023 Sep 7;14:1264321. doi: 10.3389/fphar.2023.1264321

TABLE 4.

The results of variance analysis of the main PK parameters after logarithmic transformation.

Effect factor	Postprandial trial (P)					Fasting trial (P)
	amlodipine		valsartan			amlodipine		valsartan
	LnC_max	LnAUC_0–72h	LnC_max	LnAUC_0-t	LnAUC_0-∞	LnC_max	LnAUC_0–72h	LnC_max	LnAUC_0-t	LnAUC_0-∞
Sequence	0.5097	0.0692	0.7369	0.9508	0.9463	0.6572	0.6790	0.8559	0.6989	0.6826
Formulation	0.2704	0.1295	0.8284	0.9397	0.8841	0.3032	0.8367	0.9751	0.8369	0.8922
Period	0.4570	0.6437	0.7112	0.6453	0.6545	0.0850	0.6795	0.1102	0.5317	0.5642