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. 2023 May 25;2(6):830–842. doi: 10.1016/j.gastha.2023.05.003

Figure 2.

Figure 2

Ileal enteroids retain transcriptomic signatures of biopsies in Crohn’s disease. (A) Pathway enrichment bar plot demonstrating the 15 KEGG (Kyoto Encyclopedia of Genes and Genomes) pathways most upregulated in ileal biopsies from Crohn’s disease patients, in the biopsies, as well as in enteroids. ★ indicates a pathway deemed significantly upregulated in both biopsies and enteroids by Fisher's exact test. (B) Gene set enrichment analysis plots for the chemokine signaling and proteasome KEGG pathways, in both ileal biopsies and enteroids.