Table 2.
Clinical characteristics of peritoneal dialysis patients with and without LVH-progression.
| Without LVH-progression N = 166 |
With LVH-progression N = 112 |
p Value | |
|---|---|---|---|
| Demographics | |||
| Age | 54.88 ± 16.92 | 57.32 ± 15.91 | .228 |
| Male, n (%) | 96 (57.8%) | 72 (64.3%) | .280 |
| BMI (kg/m2) | 23.62 ± 3.65 | 23.85 ± 4.04 | .623 |
| PD duration (months) | 24.67 (23.89, 30.49) | 24.90 (23.89, 36.40) | .498 |
| History of smoking | 33 (19.9%) | 22 (19.6%) | .961 |
| History of diabetes | 40 (24.1%) | 28 (25.0%) | .864 |
| Use of statins | 92 (57.1%) | 73 (65.2%) | .182 |
| Use of hypotensive drugs | 151 (93.8%) | 107 (95.5%) | .533 |
| SBP (mmHg) | 129 (118, 140) | 140 (120, 150) | .005 |
| DBP (mmHg) | 80 (70, 88) | 80 (70, 90) | .117 |
| MAP (mmHg) | 95.63 ± 12.83 | 100.05 ± 16.11 | .012 |
| LVMI (cm) | 50.17 ± 14.33 | 65.34 ± 20.13 | <.001 |
| LVIDd (cm) | 4.70 (4.30, 5.10) | 5.05 (4.65, 5.50) | <.001 |
| PWT (cm) | 1.00 (0.90, 1.10) | 1.10 (1.00, 1.20) | <.001 |
| IVST (cm) | 1.10 (0.90, 1.20) | 1.20 (1.10, 1.30) | <.001 |
| LVEF (%) | 66.0 (63.0, 72.0) | 66.0 (61.5, 71.0) | .347 |
| E/A | 0.68 (0.57, 0.84) | 0.69 (0.61, 0.84) | .632 |
| Dialysis-related variables | |||
| nPCR (g/kg/24 h) | 0.87 (0.75, 1.04) | 0.90 (0.79, 1.02) | .529 |
| Total Ccr (L/week) | 54.54 (47.38, 68.94) | 52.22 (47.07, 66.80) | .423 |
| Residual renal Ccr (L/week) | 11.11 (0.00, 34.87) | 8.74 (0.00, 28.80) | .979 |
| Total Kt/V | 1.82 (1.62, 2.08) | 1.75 (1.54, 1.95) | .066 |
| Residual renal Kt/V | 0.20 (0, 0.71) | 0.16 (0, 0.54) | .977 |
| Glucose absorption (g/24 h) | 85.35 (67.18, 113.35) | 87.70 (69.6, 119.14) | .444 |
| Volume of dialysate (per 1000 mL/24 h) | 8.08 (6.11, 9.07) | 7.94 (6.06, 8.90) | .702 |
| Biochemical parameters | |||
| Hemoglobin (g/L) | 108.5 ± 15.4 | 102.8 ± 19.1 | .007 |
| Serum iron (μmol/L) | 13.05 (10.1, 16.95) | 11.6 (9.10, 15.0) | .054 |
| TSAT (%) | 32.0 (25.0, 41.0) | 28.0 (21.5, 36.0) | .005 |
| Ferritin (ng/mL) | 229.5 (152.0, 326.6) | 179.5 (106.8, 295.0) | .011 |
| Albumin (g/L) | 36.3 ± 5.6 | 35.6 ± 5.4 | .426 |
| Calcium (mmol/L) | 2.25 ± 0.28 | 2.24 ± 0.22 | .715 |
| Phosphate (mmol/L) | 1.49 ± 0.42 | 1.60 ± 0.04 | .037 |
| iPTH (per 10 pg/mL) | 266.6 (153.0, 428.0) | 269.5 (183.0, 435.5) | .352 |
| FBG (mmol/L) | 5.1 (4.6, 6.2) | 5.3 (4.9, 6.1) | .815 |
| Serum insulin (mU/L) | 13.2 (8.7, 19.1) | 11.6 (7.9, 16.6) | .068 |
| CHO (mmol/L) | 4.34 ± 1.13 | 4.34 ± 0.88 | .975 |
| LDL (mmol/L) | 2.09 (1.58, 2.62) | 2.24 (1.80, 2.71) | .100 |
| TG (mmol/L) | 1.84 (1.27, 2.78) | 1.57 (1.06, 2.24) | .024 |
| HDL (mmol/L) | 0.89 (0.75, 1.10) | 0.91 (0.76, 1.23) | .196 |
| ApoA1 (g/L) | 0.99 (0.87, 1.17) | 0.98 (0.86, 1,19) | .909 |
| ApoB (g/L) | 0.64 (0.56, 0.78) | 0.68 (0.57, 0.76) | .432 |
| NT-proBNP (per 1000 pg/mL) | 1.63 (0.63, 4.66) | 3.51 (1.39, 12.95) | <.001 |
| hsCRP (mg/L) | 0.94 (0.41, 3.57) | 1.31 (0.51, 4.83) | .182 |
BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; LVMI: left ventricular mass index; LVDd: left ventricular end-diastolic diameter; IVST: interventricular septum thickness; PWT: posterior wall thickness; LVEF: left ventricular ejection fraction; MWT: mean wall thickness; RWT: relative wall thickness; nPCR: normalized protein catabolic rate; Ccr: creatinine clearance; Kt/V: urea clearance; TSAT: transferrin saturation; iPTH: intact parathyroid hormone; FBG: fasting blood glucose; CHO: cholesterol; TG: triglyceride; LDL: low-density lipoprotein; HDL: high-density lipoprotein; ApoA1: apolipoprotein A1; ApoB: apolipoprotein B; NT-proBNP: N-terminal pro-brain natriuretic peptide; hsCRP: high-sensitivity C-reactive protein.