Table 2. The association between sleep duration and thyroid function.
| Model 1a | p-value | Model 2b | p-value | |
|---|---|---|---|---|
| β (95% CI) | β (95% CI) | |||
| TSH(mIU/L) | ||||
| Sleep duration(h) | 0.056(0.023,0.089) | 0.001 | 0.029(-0.011,0.068) | 0.149 |
| categories | ||||
| <7 h | Reference | Reference | ||
| 7–9 h | 0.110(0.022,0.198) | 0.016 | -0.002(-0.108,0.103) | 0.962 |
| >9 h | 0.319(0.022,0.616) | 0.036 | 0.328(-0.068,0.725) | 0.101 |
| p for trend | 0.005 | 0.624 | ||
| FT3(pg/mL) | ||||
| Sleep duration(h) | -0.021(-0.032,-0.009) | <0.001 | -0.017(-0.028,-0.006) | 0.005 |
| categories | ||||
| <7 h | Reference | Reference | ||
| 7–9 h | -0.060(-0.098,-0.023) | 0.002 | -0.046(-0.083,-0.009) | 0.016 |
| >9 h | -0.102(-0.176,-0.027) | 0.009 | -0.072(-0.141,-0.002) | 0.044 |
| p for trend | <0.001 | 0.013 | ||
| FT4(ng/dL) | ||||
| Sleep duration(h) | 0.002(-0.001,0.006) | 0.169 | 0.001(-0.004,0.005) | 0.745 |
| categories | ||||
| <7 h | Reference | Reference | ||
| 7–9 h | 0.003(-0.006,0.013) | 0.447 | -0.002(-0.012,0.009) | 0.750 |
| >9 h | 0.027(0.001,0.054) | 0.045 | 0.012(-0.021,0.045) | 0.461 |
| p for trend | 0.192 | 0.935 | ||
| TT3(ng/dL) | ||||
| Sleep duration(h) | -0.433(-1.052,0.185) | 0.166 | -0.244(-0.866,0.378) | 0.430 |
| categories | ||||
| <7 h | Reference | Reference | ||
| 7–9 h | -1.594(-3.373,0.184) | 0.078 | -0.684(-2.385,1.017) | 0.418 |
| >9 h | -1.540(-6.769,3.688) | 0.556 | -2.628(-6.544,1.289) | 0.181 |
| p for trend | 0.065 | 0.320 | ||
| TT4(ug/dL) | ||||
| Sleep duration(h) | 0.015(-0.025,0.055) | 0.449 | 0.020(-0.023,0.064) | 0.352 |
| categories | ||||
| <7 h | Reference | Reference | ||
| 7–9 h | -0.007(-0.117,0.102) | 0.893 | 0.032(-0.093,0.158) | 0.601 |
| >9 h | 0.280(0.049,0.510) | 0.018 | 0.140(-0.109,0.389) | 0.259 |
| p for trend | 0.658 | 0.472 | ||
| TPOAb(IU/mL) | ||||
| Sleep duration(h) | 0.360(-2.042,2.762) | 0.764 | -0.554(-3.771,2.664) | 0.728 |
| categories | ||||
| <7 h | Reference | Reference | ||
| 7–9 h | -1.565(-8.009,4.880) | 0.628 | -4.777(-12.091,2.536) | 0.192 |
| >9 h | -2.458(-13.876,8.961) | 0.667 | -1.471(-19.320,16.379) | 0.867 |
| p for trend | 0.591 | 0.214 | ||
| TgAb (IU/mL) | ||||
| Sleep duration(h) | 0.371(-0.415,1.157) | 0.348 | -0.056(-1.057,0.946) | 0.910 |
| categories | ||||
| <7 h | Reference | Reference | ||
| 7–9 h | 0.417(-2.459,3.294) | 0.772 | -0.512(-3.899,2.875) | 0.759 |
| >9 h | 2.082(-7.351,11.514) | 0.659 | 1.865(-12.566,16.296) | 0.793 |
| p for trend | 0.705 | 0.875 | ||
| Tg (ng/mL) | ||||
| Sleep duration(h) | -0.292(-1.271,0.687) | 0.552 | -0.020(-1.192,1.152) | 0.973 |
| categories | ||||
| <7 h | Reference | Reference | ||
| 7–9 h | -0.997(-3.006,1.012) | 0.323 | 0.076(-1.992,2.144) | 0.941 |
| >9 h | 1.044(-2.203,4.291) | 0.521 | 0.514(-3.986,5.013) | 0.817 |
| p for trend | 0.435 | 0.908 |
a Model 1: no covariates were adjusted.
b Model 2: age, gender, race/ethnicity, poverty-to-income ratio, marital, body mass index, alcohol use, smoke, urinary iodine concentration, sleep disorder(ever told doctor had trouble sleeping or ever told by doctor have sleep disorder) were adjusted.
Abbreviations: TSH, thyroid-stimulating hormone; FT3, free triiodothyronine; FT4, free thyroxine; TT3, total T3; TT4, total T4; TPOAb, anti-thyroid peroxidase antibody; TgAb, anti-thyroglobulin antibody; Tg, thyroglobulin.