Table 1.
Clinical and biological characteristics of the asthmatic patients.
| Variables | Blomia + N1 = 103 | Blomia- N2 = 55 | p |
|---|---|---|---|
| Age (Years, median, IQR)* | 7 [5–11] | 3 [2–5] | <0.001 |
| Sex F (n, %) | 37 (36) | 21 (38) | 0.8 |
| Medical history prior to follow-up | |||
| Abnormal growth (n, %) | 22 (21) | 8 (15) | 0.3 |
| Psychomotor delay (n, %) | 4 (4) | 1 (2) | 0.5 |
| Associated pathology (n, %) | 101 (98) | 43 (78) | 0.001 |
| Asthma control at baseline (n, %) | 19 (18) | 9 (16) | 0.7 |
| Ongoing of background treatment at the beginning of follow-up | 33 (32) | 15 (27) | 0.5 |
| Nocturnal cough (n, %) | 68 (66) | 32 (58) | 0.3 |
| Morning cough (n, %) | 33 (32) | 16 (29) | 0.7 |
| Exertion-induced asthma (n, %) | 59 (57) | 24 (44) | 0.2 |
| Diurnal symptoms (n, %) | 10 (10) | 3 (5) | 0.4 |
| Annual number of exacerbations before follow-up (median, IQR) | 4 [3–7] | 4 [3–6] | 0.9 |
| Annual number of hospitalizations before follow-up (median, IQR) | 0 [0–1] | 0 [0–1] | 0.9 |
| Follow-up outcomes | |||
| Asthma control/follow-up (n, %) | 0.09 | ||
| Controlled asthma | 52 (50) | 24 (44) | |
| Partially controlled asthma | 39 (38) | 19 (35) | |
| Uncontrolled asthma | 6 (6) | 4 (7) | |
| Lost to follow-up | 6 (6) | 8 (15) | |
| Final change (n, %) | 0.4 | ||
| Normal progression | 83 (81) | 43 (78) | |
| Poor compliance | 10 (10) | 4 (7) | |
| Lost to follow-up | 10 (10) | 8 (15) | |
| Asthma severity (n, %) | 0.8 | ||
| In remission | 1 (1) | 3 (5) | |
| Intermittent | 19 (18) | 6 (11) | |
| Mild persistent | 50 (49) | 27 (49) | |
| Moderate persistent | 33 (32) | 18 (33) | |
| Severe persistent | 0 (0) | 1 (2) | |
| Annual number of crises after 1 year of follow-up (median, IQR) | 0 [0–1] | 1 [0–1] | 0.2 |
| Main identified allergens | |||
| D. pteronyssinus (n, %) | 97 (94) | 8 (15) | <0.001 |
| D. farinae (n, %) | 97 (94) | 6 (11) | <0.001 |
| Cockroaches (n, %) | 57 (55) | 8 (15) | 0.01 |
| Aspergillus fumigatus (n, %) | 14 (14) | 0 | 0.9 |
| Alternaria alternate (n, %) | 15 (15) | 0 | 0.8 |
IQR, interquartile range.
*The structural age groups used for analysis are infants (0–3 years), children (4–12 years) and adolescents (>12 years).