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. Author manuscript; available in PMC: 2024 Feb 17.
Published in final edited form as: N Engl J Med. 2023 Jul 18;389(7):602–611. doi: 10.1056/NEJMoa2302368

Table 1.

Demographic and Clinical Characteristics of the Participants at Baseline.*

Characteristic MIND Diet (N = 301) Control Diet (N = 303)
Demographic
Age — yr 70.4±4.2 70.4±4.2
Male sex — no. (%) 105 (34.9) 106 (35.0)
Race — no. (%)
 White 263 (87.4) 267 (88.1)
 Black 35 (11.6) 31 (10.2)
 Other 3 (1.0) 5 (1.7)
Education — yr 16.9±2.7 17.0±2.6
Clinical
Global cognition score 0.0±0.6 0.0±0.5
Apolipoprotein E ε4 allele carrier — no. (%) 76 (25.2) 98 (32.3)
Body-mass index§ 33.8±5.4 34.0±6.5
CES-D scale score 1.2±1.6 1.2±1.4
MIND-diet score 7.7±1.9 7.8±1.8
Medical history — no. (%)**
 Heart disease 12 (4.0) 15 (5.0)
 Stroke 9 (3.0) 5 (1.7)
 Diabetes 45 (15.0) 45 (14.9)
 Hypertension 154 (51.2) 170 (56.1)
*

Plus–minus values are means ±SD. MIND denotes Mediterranean–DASH Intervention for Neurodegenerative Delay.

Race was reported by the participants.

The global cognition score was derived from a 12-test battery. The raw scores from each test were converted to z scores, which were averaged across all tests to create the global cognition score; higher scores indicate better cognitive performance.

§

The body-mass index is the weight in kilograms divided by the square of the height in meters.

Scores on the Center for Epidemiological Studies Depression (CES-D) scale range from 0 to 10, with higher scores indicating a greater number of depressive symptoms.

MIND-diet scores were based on a 14-item food-frequency questionnaire that was devised by the investigators and designed to detect inadequate diet with respect to brain health. Scores range from 0 to 14, with lower scores indicating a less adequate diet with respect to putative brain health.

**

Medical history was reported by the participant.