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. 2023 Sep 21;6:963. doi: 10.1038/s42003-023-05335-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a ChIP-seq characterization of the ECA11 satellite-free centromere in the fibroblast cells lines from the FAANG mares (AH1 and AH2) and the FAANG stallions (AH3 and AH4). ChIP-seq reads from primary fibroblasts were mapped on the EquCab3.0_cen reference. The CENP-A enriched domains are visualized as peaks. The y-axis reports the normalized read counts whereas the x-axis reports the coordinates on the reference genome. b ChIP-seq profiles of the CENP-A binding domain on ECA11 in the fibroblast cell line (top) and in four tissues of different embryonic origin from the FAANG mares (AH1 and AH2) and FAANG stallions (AH3 and AH4). Color code refers to the embryonic origin. The y-axis reports the normalized read counts whereas the x-axis reports the coordinates on the EquCab3.0_cen reference genome. The scale of the y-axis is not the same across samples to highlight the position of the peak rather than its height. c Enrichment peaks obtained using SICER2.