(A) Restriction digest patterns of amplified urease genes of H. hepaticus isolates cultured from mice during a long-term colonization study. H. hepaticus was isolated from the mouse cecum 3 (lane 1), 6 (lane 2), 9 (lane 3), 12 (lane 4), 15 (lane 5), and 18 months (lane 6) postinoculation. Lane 7, H. hepaticus strain used for dosing; lane 8, 100-bp DNA ladder. (B) Restriction digest patterns of amplified urease genes of H. hepaticus isolated from different strains of mice housed within the same facility. Lane 1, DBA/2J; lane 2, B6D2F1/D; lane 3, BALB/J; lane 4, B6SJLF1; lane 5, BALB/cByj-nu; lane 6, BALB/cBj; lane 7, C57BL/6c-nu; lane 8, 100-bp DNA ladder.