Table 4.
Adverse events in the overall population and in the type 2 diabetes mellitus (T2DM) subgroup.
| Adverse event | Overall population (n = 123) | T2DM patients (n = 57) | ||
|---|---|---|---|---|
| Any grade (%) | Grade 3 (%) | Any grade (%) | Grade 3 (%) | |
| Fatigue | 69 (56.1) | 0 | 32 (56.1) | 1 (1.8) |
| Acneiform rash | 67 (54.5) | 3 (2.4) | 30 (52.6) | 3 (5.3) |
| Hypomagnesemia | 49 (39.8) | 1 (0.8) | 23 (40.4) | 2 (3.5) |
| Desquamation | 31 (25.2) | 1 (0.8) | 12 (21.1) | 1 (1.8) |
| Mucositis | 16 (13) | 1 (0.8) | 6 (10.5) | 0 |
| Nail disorders | 13 (10.6) | 0 | 5 (8.8) | 0 |
| Pruritis | 10 (8.1) | 0 | 4 (7) | 0 |
| Nausea | 8 (6.5) | 0 | 3 (5.3) | 0 |
| Infusion reaction | 5 (4.1) | 0 | 2 (3.5) | 0 |
| Muscle weakness | 5 (4.1) | 0 | 2 (3.5) | 0 |
| Diarrhea | 5 (4.1) | 1 (0.8) | 2 (3.5) | 0 |