Figure 7.

Absence of corpora lutea in the atrophied Egr1^d/d ovary. (a) Hematoxylin and eosin stained section of the Egr1^f/+ ovary; a corpus luteum is indicated by CL. (b) Similarly stained Egr1^d/d ovarian tissue section; note the absence of CLs. Also note the diminished size of the Egr1^d/d ovary compared with the Egr1^f/+ ovary shown in (a). Scale bar in (a) applies to (b). The histological data are representative of five adult mice per genotype. (c) Field of view shows luteal cells within the CL of an Egr1^f/+ ovary. (d) Image shows an antral follicle within the Egr1^d/d ovary; note the juxtaposed hemorrhagic area indicated by the white arrowhead. Scale bar in (c) applies to (d). (e) and (f) represent higher magnification images of regions in (c) and (d) respectively. Again, note the hemorrhagic areas in the Egr1^d/d ovary (white arrowhead). Scale bar in (e) applies to (f).