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. 2023 Jul 15;15:10–21. doi: 10.1016/j.aninu.2023.02.012

Fig. 7.

Fig. 7

Comprehensive response of gene expression and metabolic pathways in rumen epithelial to the introduction of BHBA and the interaction between them. The red arrows represent activation, and the blue arrows represent inhibition. BHBA = β-hydroxybutyric acid; NADH = nicotinamide adenine dinucleotide; SLC16A1 = solute carrier family 16 member 1; SLC16A3 = solute carrier family 16 member 3; NDUFC1 = NADH:ubiquinone oxidoreductase subunit C1; NDUFB4 = NADH:ubiquinone oxidoreductase subunit B4; NDUFB10 = NADH:ubiquinone oxidoreductase subunit B10; NDUFA11 = NADH:ubiquinone oxidoreductase subunit A11; NDUFA1 = NADH:ubiquinone oxidoreductase subunit A1; HMGCL = 3-hydroxy-3-methylglutaryl-CoA lyase; HMGCS2 = 3-hydroxy-3-methylglutaryl-CoA synthase isoform 2; BDH1 = β-hydroxybutyrate dehydrogenase-1; PPARA = peroxisome proliferator-activated receptor alpha; ATP5ME = ATP synthase membrane subunit e; ATP5PO = ATP synthase peripheral stalk subunit OSCP; ATP5PF = ATP synthase peripheral stalk subunit F6.