. 2023 Sep 8;14:1209224. doi: 10.3389/fmicb.2023.1209224

Table 2.

Broth microdilution results of the 19 P. aeruginosa isolates against ciprofloxacin and levofloxacin before and after induction of resistance.

			MIC (μg/mL)
Isolates codes	Before induction		After induction		# of passages*
Isolates codes	Antimicrobial IG	MIC (μg/mL)	Ciprofloxacin	Levofloxacin	# of passages*
PSA-154	Ciprofloxacin	0.125	256	>512	4
PSA-154	Levofloxacin	0.5	32	256	3
PSA-021	Ciprofloxacin	<0.0625	32	1	5
PSA-021	Levofloxacin	0.25	16	32	4
PSA-173b	Ciprofloxacin	0.25	64	64	3
PSA-173b	Levofloxacin	0.5	16	64	3
PSA-173a	Ciprofloxacin	0.25	32	64	3
PSA-173a	Levofloxacin	0.5	16	32	3
PSA-115	Ciprofloxacin	0.125	32	64	4
PSA-115	Levofloxacin	0.5	8	32	3
PSA-276	Ciprofloxacin	0.125	16	16	4
PSA-276	Levofloxacin	0.5	32	256	3
PSA-242	Ciprofloxacin	0.25	16	16	3
PSA-242	Levofloxacin	0.5	8	64	3
PSA-025	Ciprofloxacin	0.125	256	512	4
PSA-025	Levofloxacin	0.5	4	32	3
PSA-026	Ciprofloxacin	0.25	32	64	3
PSA-026	Levofloxacin	0.5	16	64	3
PSA-186	Ciprofloxacin	0.125	32	128	4
PSA-186	Levofloxacin	0.5	32	128	3
PSA-118a	Ciprofloxacin	0.25	128	>512	3
PSA-118a	Levofloxacin	0.5	32	128	3
PSA-192	Ciprofloxacin	0.125	16	32	4
PSA-192	Levofloxacin	0.25	2	32	4
PSA-182	Ciprofloxacin	0.125	16	32	4
PSA-182	Levofloxacin	0.5	1	16	3
PSA-058	Ciprofloxacin	0.125	32	32	4
PSA-058	Levofloxacin	0.5	8	32	3
PSA-285b	Ciprofloxacin	0.125	32	64	4
PSA-285b	Levofloxacin	0.5	4	32	3
PSA-113a	Ciprofloxacin	0.25	128	128	3
PSA-113a	Levofloxacin	0.5	16	64	3
PSA-124	Ciprofloxacin	0.25	16	16	3
PSA-124	Levofloxacin	0.5	16	16	3
PSA-092	Ciprofloxacin	0.125	64	128	4
PSA-092	Levofloxacin	0.25	8	16	4
PSA-146b	Ciprofloxacin	0.125	32	64	4
PSA-146b	Levofloxacin	0.5	16	32	3

IG, induced against; *, each passage represents a 2-fold increase in the MIC and the numbers indicate the passages required to reach each antibiotic breakpoint.