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. 2023 Sep 8;10:1188105. doi: 10.3389/fvets.2023.1188105

Figure 5.

Figure 5

Histopathological findings in CePV-1 and HV coinfected skin lesion from case 9. (A) Focal irregular arrangement of acidophilic keratinocytes with both basophilic INIBs and small round amphophilic ICIBs in stratum spinosum. Multifocal mild to moderate ICI in dermal papillae. Asterisk indicates the affected area of the stratum spinosum. H and E, ×20. (B) Detail of irregular-shaped keratinocytes with small vacuolizations and prominent basophilic INIBs (right upper arrows) and small round pinpoint amphophilic ICIBs (lower left arrow). Lower inset: zoomed-in image of a keratinocyte with both INIBS and ICIBs. H and E, ×60. (C) Focal delimited area with abnormal acidophilic necrotic keratinocytes in the basal area of a dermal papilla associated to a combined neutrophilic and eosinophilic ICI. H and E, ×20.