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. Author manuscript; available in PMC: 2023 Sep 22.
Published in final edited form as: Biosci Trends. 2023 Mar 9;17(2):126–135. doi: 10.5582/bst.2023.01022

Figure 2: ERp57 was identified as an Hsp70-independent PGRN- and ND7-binding molecule.

Figure 2:

(A) The scheme of the method used to identify potential molecules involved in PGRN- and ND7-mediated regulation of GD in Hsp70-independent manner. Immunoprecipitation was performed with His antibody from His-tagged PGRN and His-tagged ND7 treated Hsp70 KO mouse lung epithelium cells, followed by mass spectrometry. PBS treatment was used as a control. (B) Summary of the mass spectrometry hits that specifically bound to both PGRN and ND7.