Table 3.
Outcome characteristics
|
Characteristics
|
E group (n = 46)
|
M group (n = 45)
|
χ2
|
P value
|
| Tumor response after four months (%) | 10.578 | 0.014 | ||
| CR | 18 (39.1) | 8 (17.8) | ||
| PR | 21 (45.7) | 18 (40) | ||
| SD | 4 (8.7) | 15 (33.3) | ||
| PD | 3 (6.5) | 4 (8.9) | ||
| DCR | 43 (93.5) | 41 (91.1) | 0.714 | |
| ORR | 42 (91.3) | 30 (66.7) | 8.358 | 0.004 |
| Immediate improvement of APF (%) | - | 0.485 | ||
| Yes | 43 (93.5) | 40 (88.9) | - | |
| No | 3 (6.5) | 5 (11.1) | ||
| First-time follow-up APF improvement (%) | 0.646 | 0.421 | ||
| Improved | 37 (80.4) | 33 (73.3) | ||
| Not improved | 9 (19.6) | 12 (26.7) | ||
| AFP after 4 mo [ng/mL, median (IQR)] | 28.48 (4, 257.9) | 45.25 (4.43, 359.5) | 0.045 | |
| Child-Pugh score after 4 mo (%) | 5.321 | 0.083 | ||
| A | 33 (71.7) | 23 (51.1) | ||
| B | 10 (21.7) | 20 (44.4) | ||
| C | 3 (6.6) | 2 (4.5) | ||
| OS, months (mean ± SD) | 26.2 ± 1.4 | 20.6 ± 1.1 | 10.3 | 0.004 |
| PFS, months (mean ± SD) | 16.6 ± 1.0 | 13.8 ± 0.7 | 6.3 | 0.012 |
CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progressive disease; DCR: Disease control rate; ORR: Objective response rate; APFs: Arterioportal fistulas; AFP: Alpha-fetoprotein; AP: Arterioportal; IQR: Interquartile range; OS: Overall survival; PFS: Progression-free survival.