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. 2023 Sep 8;11:1234340. doi: 10.3389/fbioe.2023.1234340

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Copyright © 2023 Vyas, Shah, Singh and Prajapati.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Biological performance of microtia chondrocytes on different scaffolds. Microtia ear tissue with an irregular shape (A), microtia chondrocytes in P0 (B), microtia chondrocytes in P3 (C), indicate similar size and morphology. The cell growth of microtia chondrocytes reveals strong proliferation ability within 3 passages (D). Fabrication of round-shaped PGA/PLA/-PCL scaffold (F–H), scanning electron microscopy shows that after hot compressing, the multilayer structure of PCL (I) disappears and embeds with PGA fibers (J). Gross view, optical observation, and scan electron microscopy show that microtia chondrocytes behave similarly in control group (K1-K5) and exp group (L1-L5)v with no significant difference in cell adhesion efficiency (E) after 24 h between the two groups. Reproduce with permission from (Yin et al., 2020) under Right Link share.