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. 2023 Aug 28;14(18):3528–3539. doi: 10.1021/acschemneuro.3c00437

Figure 6.

Figure 6

Examples of binding modes. (A) and (B) Representative snapshots of CBD2115 on the V287[Q288]S289 site of PSP protofibril from the front and bottom view, respectively. (C) Vertical binding mode of MK6240 on the S4 site of the PSP protofibril (front view). (D) Parallel binding mode of MK6240 in the V2 site of the AD protofibril.