Table 2.
Variables Associated with ICU Death in Patients Supported by Extracorporeal Membrane Oxygenation in Multivariable Analysis Examining the Association of Obesity with Risk of Death in the ICU
| Odds Ratio for ICU Death (95% CI) | P Value | |
|---|---|---|
| Obesity | 0.63 (0.43–0.93) | 0.018 |
| Age, for 10-yr increase | 1.37 (1.22–1.54) | <0.001 |
| Sex, male | 0.93 (0.65–1.35) | 0.710 |
| Days of IMV before ECMO, for 1 d | 1.07 (1.03–1.11) | <0.001 |
| PEEP before ECMO, for 1 cm H2O increase | 0.95 (0.91–0.99) | 0.018 |
| pH before ECMO, for 0.01 increase | 0.98 (0.96–0.99) | <0.001 |
| PF ratio before ECMO, for 10 mm Hg increase | 1.00 (0.94–1.06) | 0.954 |
| Use of inhaled nitric oxide before ECMO | 1.70 (1.10–2.61) | 0.017 |
| Use of NMBA before ECMO | 0.72 (0.48–1.06) | 0.010 |
| Use of prone positioning before ECMO | 0.90 (0.55–1.43) | 0.653 |
| Need for dialysis before ECMO | 1.58 (1.07–2.33) | 0.020 |
Definition of abbreviations: CI = confidence interval; ECMO = extracorporeal membrane oxygenation; IMV = invasive mechanical ventilation; NMBA = neuromuscular blocking agents; PEEP = positive end-expiratory pressure; PF = PaO2:FiO2.