Table 3.
Variables Associated with ICU Death in Patients Supported by Extracorporeal Membrane Oxygenation in Multivariable Analysis Examining the Association of Body Mass Index as a Continuous Variable with Risk of Death in the ICU
| Odds Ratio for ICU Death (95% CI) | P Value | |
|---|---|---|
| BMI, per 1 kg/m2 increase | 0.97 (0.95–1.00) | 0.023 |
| Age, for 10-yr increase | 1.36 (1.21–1.53) | <0.001 |
| Sex, male | 0.93 (0.64–1.34) | 0.690 |
| Days of IMV before ECMO, for 1 d | 1.07 (1.04–1.12) | <0.001 |
| PEEP before ECMO, for 1 cm H2O increase | 0.96 (0.92–1.00) | 0.035 |
| pH before ECMO, for 0.01 increase | 0.98 (0.97–0.99) | <0.001 |
| PF ratio before ECMO, for 10 mm Hg increase | 1.00 (0.94–1.06) | 0.951 |
| Use of inhaled nitric oxide before ECMO | 1.75 (1.13–2.70) | 0.011 |
| Use of NMBA before ECMO | 0.73 (0.49–1.08) | 0.118 |
| Use of prone positioning before ECMO | 0.87 (0.54–1.40) | 0.578 |
| Need for dialysis before ECMO | 1.62 (1.10–2.39) | 0.015 |
Definition of abbreviations: BMI = body mass index; CI = confidence interval; ECMO = extracorporeal membrane oxygenation; IMV = invasive mechanical ventilation; NMBA = neuromuscular blocking agents; PEEP = positive end-expiratory pressure; PF = PaO2:FiO2.