Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

[Preprint]. 2023 Sep 13:2023.09.11.557155. [Version 1] doi: 10.1101/2023.09.11.557155

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This work is licensed under a Creative Commons Attribution 4.0 International License, which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.

PMC Copyright notice

Figure 2: — Power comparisons of aggregate LIT (aLIT; black), unweighted LIT (ULIT; blue), and weighted LIT (wLIT; green) under (A) positive pleiotropy and (B) a mixture of positive and negative pleiotropy. The simulation study varied the correlation between traits (columns), the number of traits (rows), and the proportion of traits with an interaction term (x-axis) at a sample size of 300,000. The points represent the average across 500 simulations with a significance threshold of 5 × 10⁻⁸.