Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Sep 7;14:1243523. doi: 10.3389/fmicb.2023.1243523

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Davis, Payne, Olguin, Sanders, Clements, Stefan, Williams, Hooper, Huggins, Mucker and Ricks.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Limits of detection with infectious virus. α-A29 is used as the capture MAb, with S27 or 4B4 as the 2° MAb. S27-PE, S27-B, and 4B4-B are depicted as black circles, blue squares, and red triangles, respectively. Median fluorescence intensity (MFI) is shown as a function of virus titer in pfu/mL for MPXV strains Zaire '79 (A), Katakombe (B), US 2003 (C), and the currently circulating strain (D). Data were fit with a 4-parameter sigmoidal function. Interpolated limits of detection of the antigen assays are shown with 90% confidence intervals in (E). The 4B4 assay does not detect Clade II MPXV and is excluded from (C, D).