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. 2023 Sep 8;14:1247804. doi: 10.3389/fmicb.2023.1247804

Table 2.

Methods for carbapenemase identification.

Carbapenemase screening methods 500 (18.5) Methods for carbapenemase identification 2,692 (99.5) Molecular methods 1712 (63.6) Immunochromatography 887 (32.9)
Type n (%) Type n (%) Type n (%) Type n (%)
mCIM 409 (81.8)
mHT 50 (10)
Colorimetric 41 (8.2)
Molecular 1,571 (58.4)
IC 804 (29.8)
Sinergy-inhibitors 168 (6.2)
IC + Molecular 72 (2.7)
Molecular+S-I 66 (2.5)
IC + Sinergy-inhibitors 8 (0.3)
IC + Molecular+S-I 3 (0.1)
PCR in-house 578 (33.8)
GeneXpert Cepheid 577 (33.7)
OXVIKPND PCR assay (Progenie) 150 (8.8)
PCR Allplex Entero DR assay (Seegene) 122 (7.1)
EAZYPLEX 62 (3.6)
PCR BD MAX Xheck-points CPO 50 (2.9)
NanoSphere/Verigene 47 (2.7)
PCR CNM-Carlos III 39 (2.3)
Genie II Optigene 26 (1.5)
Whole genome sequencing (Illumina) 23 (1.3)
Sanger Sequencing 18 (1.1)
PCR AMR (AB analitica) 12 (0.7)
PCR HAIN 7 (0.4)
PCR ELITECH carbas 1 (0.1)
NG Biotech (NG Test Carba-5) 381 (43)
OXA-48 KSeT (CORIS Bioconcept) 211 (23.8)
O.K.N.V.I RESIST5 (CORIS Bioconcept) 100 (11.3)
LETI-TEST 89 (10)
CORIS Bioconcept 66 (7.4)
Resist-3 OKN KSeT (CORIS Bioconcept) 40 (4.5)

mCIM, Modified carbapenem inactivation method; mHT, modified Hodge Test; IC, Immunochromatography; S-I, Sinergy-inhibitors.