Figure 2.

Classification of mutations in the 278 driver genes predicted in basal-like breast cancer by Moonlight. The 278 driver genes contain at least one driver mutation. Genes are in the columns while the mutation type classified by CScape-somatic is in the rows. The values in the heatmap indicate the number of driver, passenger, and unclassified mutations. The heatmap is divided into predicted oncogenes (OGs) and predicted tumor suppressor genes (TSGs). The total number of mutations and log2FC values of the driver genes are included in the heatmap. This plot was created with the plotDMA function where the input data was filtered to contain only the driver genes.