Figure 3.

The top 50 oncogenic mediators with the highest total number of mutations in basal-like breast cancer. The columns are genes and the rows are the Moonlight Gene Z-scores for the two biological processes selected in the expert-based approach: apoptosis and proliferation of cells. The genes are divided into predicted oncogenes (OGs) and predicted tumor suppressor genes (TSGs). Number of driver mutations, log2FC values, and total number of mutations of the oncogenic mediators are included in the heatmap. This plot was created with the plotMoonlight function.