Skip to main content
. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Adv Ther (Weinh). 2023 Feb 16;6(5):2200219. doi: 10.1002/adtp.202200219

Figure 4. Polymeric nanoparticles delivering SAM enable immunogenic expression of antigen greater than naked SAM.

Figure 4.

. (A) Schematic of FLuc-2A-rabies SAM dosing strategy (prime/boost). (B) Rabies Virus Neutralizing Antibody titers measured by RFFIT for top PBAE NP formulations 7–90,c12–63, 50% Sc12 and 5–3,c12–39, 30% Sc12 compared against naked SAM vaccinated and naïve serum. N=10 animals per group; Mann-Whitney test for statistical significance against naked SAM injection.