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An overview of the study design. The study cohort comprised children rapidly progressing to overt type 1 diabetes (RP) and children slowly progressing to clinical disease (SP) during the follow-up until the age of 15 years. For each child, longitudinal serum samples were drawn, corresponding to the age of 3, 6, 12, 18, 24 or ≥36 months. Moreover, the age at diagnosis of type 1 diabetes is shown in the participating children.
