Fig. 5.

Oligodendrocyte lineage cells express dopamine receptor 1 (Drd1) and dopamine receptor 2 (Drd2) transcripts in anterior regions of the corpus callosum. Computational confocal images demonstrating DAPI (A, B); Olig2 and Drd1 (A’) or Olig2 and Drd2 (B’) RNA probes; Olig2, Pdgfra and Drd1 (A’’) or Olig2, Pdgfra and Drd2 (B’’) RNA probes; and the merge of all channels (A’’’, B’’’). Arrows indicate Olig2 + /Pdgfra + cells that colocalize with dopamine receptor transcripts. Arrowheads indicate Olig2 + /Pdgfra- cells that colocalize with dopamine receptor transcripts. C Quantification of dopamine receptor transcripts by oligodendrocyte lineage cells in the anterior corpus callosum. On average, there are nearly twofold more Olig2 + /Pdgfra + cells than Olig2 + /Pdgfra- expressing dopamine receptor transcripts (F_{(1, 11)} = 13.9, **p < .01). Each black dot represents the average of 2–4 brains sections per animal